HRB-656: Phytochemistry, Pharmacology, and Introd

In this course, students learn a unique version of pharmacology that emphasizes traditional classifications based on energetics complemented with modern pharmacological principles and knowledge of the chemical structure of the active constituents in herbal medicines as identified by analytical methods. Reviewing the analytic methods used to detect plant compounds, as well as characterizing the chemical structure that contributes to both the biological activity and potential toxicity, students will enhance their understanding of the unique structural features of these phytochemicals. Knowledge of plant chemistry provides the underpinning of the student`s therapeutic approach by linking the beneficial clinical applications of herbs to classes of chemical compounds responsible for the effects. It also provides a rational for choice of methods in the preparation of herbal medicines. In addition to standard principles, less conventional aspects of pharmacology including the concepts of synergy and hormesis, along with emerging sciences such as pharmacogenomics and systems biology will be covered. Prerequisite: HRB-641. [3 credits]