PHRD-400: Biopharmaceutics and Clinical Pharmacokinetics

Biopharmaceutic and basic pharmacokinetic parameters such as absorption, istribution, metabolism and elimination, the relationship between drug concentration and clinical response, impact of patient characteristics and disease states on pharmacokinetic parameters and pharmacokinetic variations across the lifespan will be discusssed. Students will learn how to calculate and interpret pharmacokinetic parameters, discuss and explain pharmacokinetic principles, asess factors that affect drug disposition,design and adjust drug dosage regimens, and predict and explain the mechanism(s) involved in drug interactions. Pre-requisite: P-2 standing. Lecture three hours per week. [ 3 credits ]